Introduction To Nano Science & Biotechnology Module - 1 Author : Abhijit Mangaraj & Ananya Punyotoya Parida 2018 : As per BPUT syllabus.
Syllabus : Nano Science & Biotechnology Module -1(6 Hours) Fundamental and process of fabrication The world of small dimensions, Nanoscale Properties (Electrical, Optical, Chemical, Mechanical), Nanoscale visualization techniques , Electron microscopy (TEM, SEM, Cryo-SEM), Scanning probe microscopy (AFM, STM), Diffraction techniques (XRD,synchrotron),Top-down and Bottom-Up approach , nanoparticles (synthesis,properties and applications). Module-2 (12 Hours) Nano-Device and Components: Structure of carbon nanotube, Classification and physical properties of CNT, Graphene: structure, synthesis and properties, Nanophotonis (Photonic crystal in one, two and three dimensions), Quantum dot, quantum wire, Nanofluidics: nanopores and Nano capillaries, Debye length, Nanomechanics (elastic, thermal and kinetic material properties). Module-3 (10 Hours) Quantum Electronics: Coulomb blockade in nano capacitors and quantum dot circuits. Single Electron Transistor (SET), Quantum information and computing, Sprintonics devices and its classifications, Structural and optical properties of nanomaterials, Molecular Electronics, NEMS, Optical and Magnetic computer. Module -4 (10 Hours) Bio-Device and application Bio-nanostructures (nanofibers, nanotubes, nanocellulose), Biological nanomachines Ribosomes, Photosynthesis systems,Near-field Bioimaging, Nanoparticles for optical diagnosticsand Targeted Therapy,Protein nanotechnology, DNA nanotechnology, Nano robotand its application, Nanocapsule, Nanosomes, Medibots, Artifiial pancreas, Artificial Muscle,Nanoclinic for Gene delivery and photodynamic therapy Nanoparticle in cancer, Bionanomotors. ADDITIONAL MODULE (Terminal Examination-Internal) (05 hr) Nanotechnology safety and the environment,Impact of nanotechnology on society and industry, Biosensors (fabrication, functionalization, applications), Current research on nanotechnology. Books: 1. Rishal Singh, S.M. Gupta,Introduction to nanotechnologyOxford university press,(2016). 2. Paras N. Prasad, Nanophotonics, John Wiley & Sons, (2016). 3. C. M. Niemeyer, C. A. Mirkin, ―Nanobiotechnology: Concepts, Applications and Perspectives, Wiley – VCH, (2004). 2. 4 T. Pradeep, ―Nano: The Essentials, McGraw – Hill education, (2007). 4. Challa, S.S.R. Kumar, Josef Hormes, CarolaLeuschaer, Nanofabrication Towards Biomedical Applications, Techniques, Tools, Applications and Impact, Wiley – VCH, (2005). 5. Nicholas A. Kotov, ―Nanoparticle Assemblies and Superstructures, CRC, (2006). 6. David S Goodsell, “Bionanotechnology, John Wiley & Sons, (2004).
MODULE -1 The World of small Dimensions: Introduction : Questions to be considered :: • What is a nanoparticle? An example is a bucky ball – In 1985, a team led by Harry Kroto, Richard Smalley and Bob Curl discovered that carbon atoms could be made to aggregate into clusters containing 60 (or sometimes 70) atoms. They deduced that the structure of the C60 molecule was a hollow sphere, as shown in Figure below, and it was named ‘Buckminster fullerene‘ (or, more affectionately, Buckyball) because of the resemblance of the structure to the architectural designs of the architect Buckminster Fuller. 60 carbom atoms Joined in one unit. = 1nm (1 nano meter) - 10 Hydrogen atoms linked in one unit. • - How big is a nanometre? It is a million times smaller than the smallest measurement you can see on a ruler! (mm) It is a millionth of a millimetre or a billionth of a metre • How big is a nanometre? 1 nm = 10-9 m 1m = 103 mm = 106 microns 1 micron = 10-6 m
• • • A human fingernail grows 1 nanometre every second. A man’s beard grows 5 nanometres every second. This is a silver nanowire resting on a human hair. Look at a strand of your own hair and imagine how small that is… • - What is a nanoscience? Way back in 1959, a physicist named Richard Feynman shared his vision of what very small things would look like and how they would behave. In a speech at the California Institute of Technology titled “There’s Plenty of Room at the Bottom,” Feynman gave the first hint about what we now know as “nanoscience” : The study and manipulation of materials at the nanoscale . nanoscience is the study of the behavior of objects at a very small scale, roughly 1 to 100 nanometers (nm). • - Why nano? At the nanoscale, strange things happen to materials – their properties can change. Reactivity - As particles get smaller they tend to react differently with their environment than larger particles.